Invention Grant
US09278077B2 Microencapsulated bioactive agents for oral delivery and methods of use thereof
有权
用于口服递送的微囊化生物活性剂及其使用方法
- Patent Title: Microencapsulated bioactive agents for oral delivery and methods of use thereof
- Patent Title (中): 用于口服递送的微囊化生物活性剂及其使用方法
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Application No.: US14051939Application Date: 2013-10-11
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Publication No.: US09278077B2Publication Date: 2016-03-08
- Inventor: Daniel R. DeBrouse
- Applicant: Tamarisk Technologies Group, LLC
- Applicant Address: US CA Moorpark
- Assignee: TAMARISK TECHNOLOGIES GROUP, LLC
- Current Assignee: TAMARISK TECHNOLOGIES GROUP, LLC
- Current Assignee Address: US CA Moorpark
- Agency: Hovey Williams LLP
- Main IPC: A61K31/05
- IPC: A61K31/05 ; A61K9/50 ; A61K47/02 ; A61K47/10 ; A61K47/26 ; A61K47/36 ; A61K47/44 ; A61K31/035 ; A61K31/122 ; A61K31/375 ; A61K31/573 ; A61K35/745 ; A61K35/747 ; A61K38/28 ; A61K45/06

Abstract:
The presently claimed and disclosed inventive concept(s) contemplates a novel polymeric oral dosage form (transmucosal delivery vehicle) for delivery of pharmaceutical and nutriceutical bioactive agents to the mucosa and bloodstream of the intestine. The oral dosage form of the presently claimed and disclosed inventive concept(s) comprises a polymeric coating which encapsulates the bioactive agent and inhibits degradation and dissolution of the bioactive agent within the stomach and within the lumen of the intestine until after passing through the mucosal wall of the small and/or large intestine. The enzymatic degradation of the polymeric delivery vehicle containing the bioactive agent is substantially inhibited until after absorption of the polymeric delivery vehicle into blood vessels of the intestinal mucosa. It is a particular object of the presently claimed and disclosed inventive concept(s) to provide a new and improved method for enterically or intestinally encapsulating pharmaceutical and nutriceutical bioactive agent or agents for oral administration of the encapsulated bioactive agent or agents.
Public/Granted literature
- US20140037743A1 MICROENCAPSULATED BIOACTIVE AGENTS FOR ORAL DELIVERY AND METHODS OF USE THEREOF Public/Granted day:2014-02-06
Information query