Invention Grant
US09278133B2 Highly purified type A botulinum toxin preparation from infant botulism pathogen
有权
来自婴儿肉毒杆菌病原体的高纯度A型肉毒杆菌毒素制剂
- Patent Title: Highly purified type A botulinum toxin preparation from infant botulism pathogen
- Patent Title (中): 来自婴儿肉毒杆菌病原体的高纯度A型肉毒杆菌毒素制剂
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Application No.: US12447351Application Date: 2007-10-26
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Publication No.: US09278133B2Publication Date: 2016-03-08
- Inventor: Tetsuhiro Harakawa , Hirotoshi Nakano , Yasushi Torii , Yoshitaka Goto , Miho Shinmura , Sachio Okuda , Ryuji Kaji , Shunji Kosaki
- Applicant: Tetsuhiro Harakawa , Hirotoshi Nakano , Yasushi Torii , Yoshitaka Goto , Miho Shinmura , Sachio Okuda , Ryuji Kaji , Shunji Kosaki
- Applicant Address: JP Kumamoto JP Tokushima
- Assignee: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE,TOKUSHIMA UNIVERSITY
- Current Assignee: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE,TOKUSHIMA UNIVERSITY
- Current Assignee Address: JP Kumamoto JP Tokushima
- Agency: Browdy and Neimark, PLLC
- Priority: JP2006-293173 20061027
- International Application: PCT/JP2007/070927 WO 20071026
- International Announcement: WO2008/050866 WO 20080502
- Main IPC: A61K38/48
- IPC: A61K38/48 ; A61K39/08 ; A61K9/00 ; A61K47/42 ; A61K9/19
Abstract:
A novel type A botulinum toxin preparation is provided. A neuromuscular transmission blocking agent comprising as an active ingredient a highly purified type A botulinum toxin from Clostridium botulinum as infant botulism pathogen and a medicament for treating a disease with a muscle overactivity comprising as an active ingredient said toxin. In particular, the medicament of the present invention, as compared to the conventional known botulinum toxin preparations, has rapid efficacy of potential and is less diffusive and thus, having a broader safety margin, may be used as therapeutic medicament for decreasing local, muscle overactivity in a disease with a muscle overactivity.
Public/Granted literature
- US20100173841A1 Highly Purified Type A Botulinum Toxin Preparation From Infant Botulism Pathogen Public/Granted day:2010-07-08
Information query
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