Invention Grant
- Patent Title: Treatment of intracellular bacterial infection
- Patent Title (中): 细胞内细菌感染的治疗
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Application No.: US14430650Application Date: 2013-09-25
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Publication No.: US09278141B2Publication Date: 2016-03-08
- Inventor: Michael Mattey , James Chadwick
- Applicant: FIXED PHAGE LIMITED
- Applicant Address: GB Glasgow Strathclyde
- Assignee: Fixed Phage Limited
- Current Assignee: Fixed Phage Limited
- Current Assignee Address: GB Glasgow Strathclyde
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- Priority: GB1217097.3 20120925
- International Application: PCT/EP2013/069999 WO 20130925
- International Announcement: WO2014/049008 WO 20140403
- Main IPC: A61K47/48
- IPC: A61K47/48 ; A01N63/00 ; A61K35/76

Abstract:
An intracellular bacterial infection in a plant or animal is treated by administration to a plant cell or animal cell of a particle to which an infectious bacteriophage is covalently attached, wherein the particle is internalized by the cell. Particles with phage attached and compositions comprising the particles are provided. A formulation, for treatment of a bacterial infection, comprises bacteriophage, liquid carrier and adhesive, which dries so that the adhesive adheres the bacteriophage to a surface, one such formulation comprising liquid carrier: 85%-99.98% by weight; bacteriophage: 0.01%-5% by weight; and adhesive: 0.01%-10% by weight.
Public/Granted literature
- US20150250897A1 TREATMENT OF INTRACELLULAR BACTERIAL INFECTION Public/Granted day:2015-09-10
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