Invention Grant
US09278163B2 Implantable polymeric device for sustained release of dopamine agonist
有权
用于持续释放多巴胺激动剂的可植入聚合物
- Patent Title: Implantable polymeric device for sustained release of dopamine agonist
- Patent Title (中): 用于持续释放多巴胺激动剂的可植入聚合物
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Application No.: US14506426Application Date: 2014-10-03
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Publication No.: US09278163B2Publication Date: 2016-03-08
- Inventor: Rajesh A. Patel , Louis R. Bucalo , Lauren Costantini , Sofie Kleppner
- Applicant: Titan Pharmaceuticals, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Titan Pharmaceuticals, Inc.
- Current Assignee: Titan Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- Main IPC: A61L31/16
- IPC: A61L31/16 ; A61K9/00 ; A61K9/14 ; A61K9/16 ; A61K31/381 ; A61K31/4045 ; A61K31/428 ; A61K31/48 ; A61K31/485 ; A61L31/04 ; A61K31/198 ; A61L31/10 ; A61L31/12 ; A61L31/14

Abstract:
The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
Public/Granted literature
- US20150151029A1 IMPLANTABLE POLYMERIC DEVICE FOR SUSTAINED RELEASE OF DOPAMINE AGONIST Public/Granted day:2015-06-04
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