Invention Grant
- Patent Title: Intermediates of neutral endopeptidase inhibitors and preparation method thereof
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Application No.: US14739172Application Date: 2015-06-15
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Publication No.: US09278908B2Publication Date: 2016-03-08
- Inventor: David Hook , Jianguang Zhou , Yunzhong Li , Jie Ku
- Applicant: David Hook , Jianguang Zhou , Yunzhong Li , Jie Ku
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent David R. Kurlandsky
- Priority: WOPCT/CN2010/070322 20100122
- Main IPC: C07D207/267
- IPC: C07D207/267 ; C07D207/27 ; C07D207/38 ; C07C231/10 ; C07D207/26 ; C07D207/263 ; C07D207/277
Abstract:
The invention relates to a new process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a g-amino-d-biphenyl-a-methylalkanoic acid, or acid ester, backbone, such as N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof.
Public/Granted literature
- US20150274642A1 INTERMEDIATES OF NEUTRAL ENDOPEPTIDASE INHIBITORS AND PREPARATION METHOD THEREOF Public/Granted day:2015-10-01
Information query
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