Invention Grant
US09278912B2 C13-hydroxy derivatives of oleanolic acid and methods of use thereof
有权
齐墩果酸的C13-羟基衍生物及其使用方法
- Patent Title: C13-hydroxy derivatives of oleanolic acid and methods of use thereof
- Patent Title (中): 齐墩果酸的C13-羟基衍生物及其使用方法
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Application No.: US14023180Application Date: 2013-09-10
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Publication No.: US09278912B2Publication Date: 2016-03-08
- Inventor: Xin Jiang , Christopher F. Bender , Melean Visnick
- Applicant: REATA PHARMACEUTICALS, INC.
- Applicant Address: US TX Irving
- Assignee: Reata Pharmaceuticals, Inc.
- Current Assignee: Reata Pharmaceuticals, Inc.
- Current Assignee Address: US TX Irving
- Agency: Parker Highlander PLLC
- Main IPC: A61K31/343
- IPC: A61K31/343 ; A61K31/16 ; A61K31/122 ; C07C69/74 ; C07C233/58 ; C07C35/44 ; C07D307/00 ; C07C255/47 ; C07J63/00

Abstract:
Disclosed herein are novel C13-hydroxy derivatives of oleanolic acid, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds, for example, as antioxidant inflammation modulators, and compositions thereof are also provided.
Public/Granted literature
- US20140088188A1 C13-HYDROXY DERIVATIVES OF OLEANOLIC ACID AND METHODS OF USE THEREOF Public/Granted day:2014-03-27
Information query
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