Invention Grant
- Patent Title: Process for making amino acid compounds
- Patent Title (中): 制备氨基酸化合物的方法
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Application No.: US14401095Application Date: 2013-05-17
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Publication No.: US09278917B2Publication Date: 2016-03-08
- Inventor: Travis Remarchuk
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Viksnins Harris & Padys PLLP
- International Application: PCT/US2013/041687 WO 20130517
- International Announcement: WO2013/173779 WO 20131121
- Main IPC: C07C229/30
- IPC: C07C229/30 ; C07C269/06 ; C07C271/22 ; C07C67/343 ; C07C67/313 ; C07C269/04
Abstract:
The invention provides new processes for making and purifying amino acid compounds, which are useful in the preparation of AKT inhibitors used in the treatment of diseases such as cancer, including the compound (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one.
Public/Granted literature
- US20150148559A1 PROCESS FOR MAKING AMINO ACID COMPOUNDS Public/Granted day:2015-05-28
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