Invention Grant
- Patent Title: Production method of imidazole derivatives
- Patent Title (中): 咪唑衍生物的生产方法
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Application No.: US14123381Application Date: 2012-06-14
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Publication No.: US09278938B2Publication Date: 2016-03-08
- Inventor: Yoichi Kawabata , Yasuhiro Sawai , Kazuaki Kanno , Naotaka Sawada
- Applicant: Yoichi Kawabata , Yasuhiro Sawai , Kazuaki Kanno , Naotaka Sawada
- Applicant Address: JP Osaka-Shi
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka-Shi
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent David G. Conlin; Joohee Lee
- Priority: JP2011-133712 20110615
- International Application: PCT/JP2012/065795 WO 20120614
- International Announcement: WO2012/173280 WO 20121220
- Main IPC: C07D233/64
- IPC: C07D233/64 ; C07D487/04

Abstract:
The present invention provides an advantageous production method of an imidazole derivative, which is suitable for industrial production.Compound (VI) is produced by reacting compound (I) with a Grignard reagent or a magnesium reagent, and a lithium reagent, and then reacting the resulting compound with compound (V).
Public/Granted literature
- US20140100373A1 PRODUCTION METHOD OF IMIDAZOLE DERIVATIVES Public/Granted day:2014-04-10
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