Invention Grant
- Patent Title: Pyrrolidine derivatives, pharmaceutical compositions and uses thereof
- Patent Title (中): 吡咯烷衍生物,药物组合物及其用途
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Application No.: US14275873Application Date: 2014-05-12
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Publication No.: US09278954B2Publication Date: 2016-03-08
- Inventor: Niklas Heine , Martin Fleck , Bernd Nosse , Gerald Juergen Roth
- Applicant: Niklas Heine , Martin Fleck , Bernd Nosse , Gerald Juergen Roth
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Alan R. Stempel
- Priority: EP13168294 20130517
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D207/12 ; C07D401/04 ; C07D413/14 ; C07D403/14 ; C07D417/14

Abstract:
Pyrrolidine derivatives which are inhibitors of acetyl-CoA carboxylase(s) and their use in the treatment of obesity and type-2 diabetes. An exemplary compound is 2-(4-(1-[5-Chloro-6-(2-hydroxy-2-methyl-propoxy)-pyrimidin-4-yl]-(R)-pyrrolidin-3-yloxy)-phenyl)-N-cyclopropyl-propionamide.
Public/Granted literature
- US20140343083A1 Pyrrolidine derivatives, pharmaceutical compositions and uses thereof Public/Granted day:2014-11-20
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