Invention Grant
- Patent Title: Pyridyl inhibitors of hedgehog signalling
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Application No.: US12960609Application Date: 2010-12-06
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Publication No.: US09278961B2Publication Date: 2016-03-08
- Inventor: Janet L. Gunzner , Daniel Sutherlin , Mark S. Stanley , Liang Bao , Georgette M. Castanedo , Rebecca L. Lalonde , Shumei Wang , Mark E. Reynolds , Scott J. Savage , Kimberly Malesky , Michael S. Dina , Michael F. T. Koehler
- Applicant: Janet L. Gunzner , Daniel Sutherlin , Mark S. Stanley , Liang Bao , Georgette M. Castanedo , Rebecca L. Lalonde , Shumei Wang , Mark E. Reynolds , Scott J. Savage , Kimberly Malesky , Michael S. Dina , Michael F. T. Koehler
- Applicant Address: US CA South San Francisco US MA Lexington
- Assignee: GENENTECH, INC.,CURIS, INC.
- Current Assignee: GENENTECH, INC.,CURIS, INC.
- Current Assignee Address: US CA South San Francisco US MA Lexington
- Agency: Millen White Zelano and Branigan, PC
- Main IPC: C07D213/38
- IPC: C07D213/38 ; C07D417/12 ; C07D401/14 ; A61K31/44 ; C07D213/40 ; C07D213/56 ; C07D213/70 ; C07D213/75 ; C07D213/81 ; C07D213/82 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/04 ; C07F9/58
Abstract:
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.
Public/Granted literature
- US20110092461A1 PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING Public/Granted day:2011-04-21
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