Invention Grant
- Patent Title: 6-Alkynyl Pyridine
- Patent Title (中): 6-炔基吡啶
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Application No.: US14463692Application Date: 2014-08-20
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Publication No.: US09278978B2Publication Date: 2016-03-08
- Inventor: Ulrich Reiser , James Madden
- Applicant: Ulrich Reiser , James Madden
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Alan R. Stempel
- Priority: EP13181577 20130823
- Main IPC: C07D491/048
- IPC: C07D491/048 ; C07D213/75 ; C07D401/04 ; C07D401/14 ; C07D471/04 ; C07D473/00 ; C07D487/04 ; C07D401/02 ; C07D403/02 ; C07D403/14 ; A61K31/519 ; A61K31/444 ; A61K31/435
Abstract:
This invention relates to 6-alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups R1 to R5 have the meanings given in the claims and in the specification.
Public/Granted literature
- US20150057295A1 New 6-Alkynyl Pyridine Public/Granted day:2015-02-26
Information query
