Invention Grant
US09278998B2 Compositions and methods for diagnosing and/or treating influenza infection
有权
用于诊断和/或治疗流感感染的组合物和方法
- Patent Title: Compositions and methods for diagnosing and/or treating influenza infection
- Patent Title (中): 用于诊断和/或治疗流感感染的组合物和方法
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Application No.: US12829931Application Date: 2010-07-02
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Publication No.: US09278998B2Publication Date: 2016-03-08
- Inventor: Akila Jayaraman , Karthik Viswanathan , Rahul Raman , Zachary H. Shriver , Ram Sasisekharan
- Applicant: Akila Jayaraman , Karthik Viswanathan , Rahul Raman , Zachary H. Shriver , Ram Sasisekharan
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Agency: Choate, Hall & Stewart—LLP
- Agent Brenda Herschbach Jarell
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K38/16 ; C07K14/005
Abstract:
The present invention provides HA polypeptides (e.g., H1 HA polypeptides) that bind to umbrella-topology glycans, and reagents and methods relating thereto. The present invention provides binding agents that bind to HA polypeptides (e.g., H1 HA polypeptides), and reagents and methods relating thereto. The present invention provides interfering agents that inhibit the binding of HA polypeptides (e.g., H1 HA polypeptides) to HA receptors, and reagents and methods relating thereto. The present invention provides compositions and methods for treating, preventing, and/or diagnosing influenza infection utilizing HA polypeptides, HA polypeptide binding agents, HA polypeptide interfering agents, and/or vaccine compositions comprising any of the foregoing.
Public/Granted literature
- US20110033490A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND/OR TREATING INFLUENZA INFECTION Public/Granted day:2011-02-10
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