Invention Grant
- Patent Title: FILIP1L nucleic acid fragments
- Patent Title (中): FILIP1L核酸片段
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Application No.: US13952192Application Date: 2013-07-26
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Publication No.: US09279009B2Publication Date: 2016-03-08
- Inventor: Steven K. Libutti , Mijung Kwon , Anita Tandle
- Applicant: Steven K. Libutti , Mijung Kwon , Anita Tandle
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07K14/47 ; G01N33/574 ; A61K35/13
Abstract:
A purified DOC1 polypeptide comprising a fragment of SEQ ID NO:1 is provided, wherein the DOC1 polypeptide is not the full-length DOC1 polypeptide sequence. A method of inhibiting angiogenesis in a subject is provided comprising administering to a subject a nucleic acid encoding a DOC1 polypeptide, whereby a cell in the subject produces the DOC1 polypeptide, thus inhibiting angiogenesis. A method of inhibiting tumor growth in a subject is provided comprising administering to a subject a nucleic acid encoding a DOC1 polypeptide, whereby a cell in the subject produces the DOC1 polypeptide, thus inhibiting tumor growth.
Public/Granted literature
- US20140039041A1 FILIP1L COMPOSITIONS AND METHODS FOR TREATING CANCER Public/Granted day:2014-02-06
Information query
