Invention Grant
- Patent Title: Immortalization of epithelial cells and methods of use
- Patent Title (中): 上皮细胞的永生化和使用方法
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Application No.: US13885078Application Date: 2011-11-11
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Publication No.: US09279106B2Publication Date: 2016-03-08
- Inventor: Richard Schlegel , Xuefeng Liu
- Applicant: Richard Schlegel , Xuefeng Liu
- Applicant Address: US DC Washington
- Assignee: Georgetown University
- Current Assignee: Georgetown University
- Current Assignee Address: US DC Washington
- Agency: Morgan, Lewis & Bockius LLP
- International Application: PCT/US2011/060378 WO 20111111
- International Announcement: WO2012/065067 WO 20120518
- Main IPC: A61K35/36
- IPC: A61K35/36 ; A61P17/00 ; A61P17/02 ; C12N5/071 ; C12Q1/68 ; G01N33/50
Abstract:
The present invention is directed towards methods of culturing non-keratinocyte epithelial cells, with the methods comprising culturing non-keratinocyte epithelial cells in the presence of feeder cells and a calcium-containing medium while inhibiting the activity of Rho kinase (ROCK) in the feeder cell, the non-keratinocyte epithelial cells or both during culturing.
Public/Granted literature
- US20130309681A1 Immortalization of Epithelial Cells and Methods of Use Public/Granted day:2013-11-21
Information query
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