Invention Grant
- Patent Title: Mid-infrared imaging of microarrays
- Patent Title (中): 微阵列的中红外成像
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Application No.: US13879157Application Date: 2011-10-14
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Publication No.: US09279770B2Publication Date: 2016-03-08
- Inventor: Magdi M. Mossoba , Sufian Al-Khaldi , Brianna Schoen , Betsy Jean Yakes
- Applicant: Magdi M. Mossoba , Sufian Al-Khaldi , Brianna Schoen , Betsy Jean Yakes
- Applicant Address: US DC Washington
- Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Current Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Current Assignee Address: US DC Washington
- Agency: Cantor Colburn LLP
- International Application: PCT/US2011/056248 WO 20111014
- International Announcement: WO2012/051476 WO 20120419
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12M1/34 ; C07H21/02 ; C07H21/04 ; G01J5/00 ; G01J3/00 ; C40B30/04 ; G01N21/75
Abstract:
Described herein are methods for mid-infrared imaging of nucleic acid microarrays by employing mid-infrared reflective labels combined with detection in the reflection mode. The methods described herein provide intrinsic image contrast, and permit detection of DNA microarray hybridization on infrared absorbing substrates such as glass slides.
Public/Granted literature
- US20140148352A1 MID-INFRARED IMAGING OF MICROARRAYS Public/Granted day:2014-05-29
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