Invention Grant
US09290484B2 Furyl and thienyl triazole derivatives and therapeutic uses thereof
有权
呋喃基和噻吩基三唑衍生物及其治疗用途
- Patent Title: Furyl and thienyl triazole derivatives and therapeutic uses thereof
- Patent Title (中): 呋喃基和噻吩基三唑衍生物及其治疗用途
-
Application No.: US13774231Application Date: 2013-02-22
-
Publication No.: US09290484B2Publication Date: 2016-03-22
- Inventor: Jeffrey D. Laskin , Diane E. Heck , Geraldine Guillon , Thomas Finetti , Angela Hunter , Christophe Guillon , Robert D. Rapp , Anna M. Vetrano , Ned D. Heindel
- Applicant: University of Medicine and Dentistry of New Jersey
- Applicant Address: US NJ New Brunswick US PA Bethlehem
- Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY,LEHIGH UNIVERSITY
- Current Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY,LEHIGH UNIVERSITY
- Current Assignee Address: US NJ New Brunswick US PA Bethlehem
- Agency: Fox Rothschild LLP
- Main IPC: C07D249/14
- IPC: C07D249/14 ; C07D249/12 ; A61K31/42 ; C07D409/04 ; C07D405/04 ; C07D405/14 ; C07D409/12 ; C07D409/14 ; A61K31/4196
Abstract:
Nitric oxide biosynthesis-inhibiting anti-inflammatory and anti-microbial compounds of Formula (3) and Formula (4) wherein R1 and R2 are independently selected from optionally substituted thienyl, optionally substituted furyl, optionally substituted —CH═CH-thienyl and optionally substituted —CH═CH-furyl, provided that R2 is substituted with as nitro group Treatment methods utilizing the compounds, and methods of synthesis of the compounds are also disclosed.
Public/Granted literature
- US20140243381A1 FURYL AND THIENYL TRIAZOLE DERIVATIVES AND THERAPEUTIC USES THEREOF Public/Granted day:2014-08-28
Information query
