A drive system is provided for rotating and translating a biopsy member. The drive system includes housing having an opening having housing threads. A device gear within the opening has device gear threads that mate with the housing threads. A biopsy member is fixed to the device gear. The device gear threads have gear teeth that mate with pinion teeth that are disposed circumferentially on a pinion. A drive is configured to rotate the pinion thereby rotating and translating the biopsy member relative to the housing.