Invention Grant
- Patent Title: sGCalphal inhibiting compositions
- Patent Title (中): sGCalphal抑制组合物
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Application No.: US14069790Application Date: 2013-11-01
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Publication No.: US09301991B2Publication Date: 2016-04-05
- Inventor: Lirim Shemshedini , Shao-Yong Chen , Changmeng Cai , Chen-Lin Hsieh
- Applicant: The University of Toledo
- Applicant Address: US OH Toledo
- Assignee: The University of Toledo
- Current Assignee: The University of Toledo
- Current Assignee Address: US OH Toledo
- Agency: MacMillan, Sobanski & Todd, LLC
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K38/10 ; C07K7/06 ; C07K7/08 ; C07K5/103 ; C07K5/083 ; A61K38/08 ; A61K38/06 ; A61K38/07 ; A61K31/7048 ; C07K5/11 ; C07K5/107 ; C12N9/88 ; A61K38/00
Abstract:
The present invention provides materials and methods useful to treat various sGCα1-expressing cancers. Materials include peptides which interfere with sGCα1's pro-survival functions, thereby resulting in apoptosis of sGCα1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.
Public/Granted literature
- US20140088023A1 sGCalpha1 Inhibiting Compositions, and Methods of Treatment of Cancers Therewith Public/Granted day:2014-03-27
Information query
IPC分类:
