An interactive electronic greeting card with pop-up feature includes a pocket or cavity which houses various electronic and mechanical components and a pop-up element. In a first position, the pop-up element is substantially contained within the greeting card pocket or cavity. When the push button is depressed, the pop-up element is ejected or “pops up” out of the greeting card pocket or cavity, revealing a greeting or other printed indicia, a mobile object or a gift card attached thereto. The push button also initiates playback of a pre-loaded digital audio file, which may be a spoken message, a sound, a song, music or other such audio recording.