Invention Grant
US09302967B2 Substituted cathechols as inhibitors of IL-4 and IL-5 for the treatment of bronchial asthma
有权
取代的导管胆固醇作为IL-4和IL-5的抑制剂用于治疗支气管哮喘
- Patent Title: Substituted cathechols as inhibitors of IL-4 and IL-5 for the treatment of bronchial asthma
- Patent Title (中): 取代的导管胆固醇作为IL-4和IL-5的抑制剂用于治疗支气管哮喘
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Application No.: US14110869Application Date: 2012-04-11
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Publication No.: US09302967B2Publication Date: 2016-04-05
- Inventor: Santu Bandyopadhyay , Balaram Ghosh , Parasuraman Jaisankar , Bikas Chandra Pal , Siddhartha Roy , Bholanath Paul , Arjun Ram , Ulaganathan Mabalirajan , Nahid Ali , Arun Bandopadhyay , Aditya Konar , Jayashree Bagchi Chakraborty , Indrani Choudhury Mukherjee , Jaydeep Chaudhuri , Sanjit Kumar Mahato , Anirban Manna , Roma Sinha , Pradyot Bhattacharya , Jayaraman Vinayagam , Deba Prasad Jana , Sushovan Chowdhury
- Applicant: Santu Bandyopadhyay , Balaram Ghosh , Parasuraman Jaisankar , Bikas Chandra Pal , Siddhartha Roy , Bholanath Paul , Arjun Ram , Ulaganathan Mabalirajan , Nahid Ali , Arun Bandopadhyay , Aditya Konar , Jayashree Bagchi Chakraborty , Indrani Choudhury Mukherjee , Jaydeep Chaudhuri , Sanjit Kumar Mahato , Anirban Manna , Roma Sinha , Pradyot Bhattacharya , Jayaraman Vinayagam , Deba Prasad Jana , Sushovan Chowdhury
- Applicant Address: IN Rafi Marg
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN Rafi Marg
- Agency: Potter Anderson & Corroon LLP
- Priority: IN01032/DEL/2011 20110411
- International Application: PCT/IB2012/051757 WO 20120411
- International Announcement: WO2012/140574 WO 20121018
- Main IPC: A61K31/14
- IPC: A61K31/14 ; A61K31/05 ; C07C39/19 ; A61K31/15 ; A61K31/215 ; A61K31/277 ; A61K31/36 ; C07C69/017 ; C07C69/732 ; C07C251/40 ; C07C251/66 ; C07C255/36 ; C07D317/50
Abstract:
The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation.
Public/Granted literature
- US20140135393A1 SUBSTITUTED CATHECHOLS AS INHIBITORS OF IL-4 AND IL-5 FOR THE TREATMENT BRONCHIAL ASTHMA Public/Granted day:2014-05-15
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