Invention Grant
US09302986B2 Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof
有权
取代的ASSAO的3-卤代烯丙胺抑制剂及其用途
- Patent Title: Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof
- Patent Title (中): 取代的ASSAO的3-卤代烯丙胺抑制剂及其用途
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Application No.: US14397931Application Date: 2013-04-05
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Publication No.: US09302986B2Publication Date: 2016-04-05
- Inventor: Mandar Deodhar , Alison Dorothy Findlay , Jonathan Stuart Foot , Wolfgang Jarolimek , Ian Alexander Mcdonald , Alan Duncan Robertson , Craig Ivan Turner
- Applicant: Boehringer Ingelheim International GmbH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- Current Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Philip I. Datlow
- International Application: PCT/AU2013/000356 WO 20130405
- International Announcement: WO2013/163675 WO 20131107
- Main IPC: C07C311/37
- IPC: C07C311/37 ; C07C235/46 ; C07C323/62 ; C07C237/30 ; C07C323/63 ; C07C311/29
Abstract:
The preparation and pharmaceutical use of substituted 3-haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula I: is described. Methods of using compounds of Formula I, or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases, ocular diseases, fibrotic diseases, diabetes-induced diseases and cancer, are also described.
Public/Granted literature
- US20150158813A1 SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF Public/Granted day:2015-06-11
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