Invention Grant
- Patent Title: NAMPT and rock inhibitors
- Patent Title (中): NAMPT和岩石抑制剂
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Application No.: US13294303Application Date: 2011-11-11
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Publication No.: US09302989B2Publication Date: 2016-04-05
- Inventor: Michael L. Curtin , Bryan K. Sorensen , Howard R. Heyman , Richard F. Clark , Kevin R. Woller , Omar J. Shah , Michael Michaelides , Chris Tse , Anil Vasudevan , Helmut Mack , Todd M. Hansen , Ramzi Sweis , Marina A. Pliushchev
- Applicant: Michael L. Curtin , Bryan K. Sorensen , Howard R. Heyman , Richard F. Clark , Kevin R. Woller , Omar J. Shah , Michael Michaelides , Chris Tse , Anil Vasudevan , Helmut Mack , Todd M. Hansen , Ramzi Sweis , Marina A. Pliushchev
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agent Glen J. Gesicki
- Main IPC: A01N43/38
- IPC: A01N43/38 ; A61K31/40 ; C07D209/44 ; C07D401/12 ; C07D401/14 ; C07D403/10 ; C07D407/12 ; C07D407/14 ; C07D413/12 ; C07D417/12 ; C07D471/04 ; C07D491/048 ; C07D495/04 ; C07D403/12 ; C07D403/14 ; C07D405/12
Abstract:
Disclosed are 1,3-dihydro-2H-isoindole compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of using the compounds to treat diseases during which NAMPT is expressed, e.g., cancer, metabolic disorders, and inflammatory disorders. Disclosed are 1,3-dihydro-2H-isoindole compounds which inhibit the activity of ROCK, compositions containing the compounds and methods of using the compounds to treat diseases during which ROCK is expressed, e.g., cancer, cardiovascular disorders, and inflammatory disorders.
Public/Granted literature
- US20120122842A1 NAMPT AND ROCK INHIBITORS Public/Granted day:2012-05-17
Information query
IPC分类:
