Invention Grant
- Patent Title: Continuous arycyclic compound
- Patent Title (中): 连续的芳环化合物
-
Application No.: US13994543Application Date: 2011-12-16
-
Publication No.: US09302996B2Publication Date: 2016-04-05
- Inventor: Osamu Sakurai , Kunio Saruta , Norimitsu Hayashi , Takashi Goi , Kenji Morokuma , Hidekazu Tsujishima , Hiroaki Sawamoto , Hiroaki Shitama , Ritsuo Imashiro
- Applicant: Osamu Sakurai , Kunio Saruta , Norimitsu Hayashi , Takashi Goi , Kenji Morokuma , Hidekazu Tsujishima , Hiroaki Sawamoto , Hiroaki Shitama , Ritsuo Imashiro
- Applicant Address: JP Osaka-shi
- Assignee: MITSUBISHI TANABE PHARMA CORPORATION
- Current Assignee: MITSUBISHI TANABE PHARMA CORPORATION
- Current Assignee Address: JP Osaka-shi
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/JP2011/079958 WO 20111216
- International Announcement: WO2012/081736 WO 20120621
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D211/72 ; C07D233/64 ; C07D401/04 ; C07D401/10 ; C07D401/14 ; C07D403/04 ; C07D403/10 ; C07D405/14

Abstract:
This is to provide a continuous arycyclic compound having a DGAT1 inhibitory activity, and useful for prophylaxis and/or treatment of obesity or hyperlipidemia caused by obesity, hypertriglyceridemia, lipid metabolism disorder, fatty liver, hypertension, arteriosclerosis, diabetes, etc., as well as to provide a DGAT1 inhibitor comprising the continuous arycyclic compound or a pharmaceutically acceptable salt thereof as an effective ingredient. Disclosed is the continuous arycyclic compound is represented by the formula: wherein the substituents in the formula are the same as defined in the specification, or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20130261128A1 CONTINUOUS ARYCYCLIC COMPOUND Public/Granted day:2013-10-03
Information query