Invention Grant
- Patent Title: Purification of taxanes
- Patent Title (中): 紫杉烷的纯化
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Application No.: US14188416Application Date: 2014-02-24
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Publication No.: US09303004B2Publication Date: 2016-04-05
- Inventor: James H. Johnson , T. G. Sambandam , Barry J. Hand , Christopher D. Howe , Roland R. Franke , Brian A. Bucher , John S. Juchum , Rex T. Gallagher , Marc A. Plante , Edward M. Desimone, III , Dong S. Yang
- Applicant: Phyton Holdings LLC
- Applicant Address: US TX San Antonio
- Assignee: Phyton Holdings, LLC
- Current Assignee: Phyton Holdings, LLC
- Current Assignee Address: US TX San Antonio
- Agency: Norton Rose Fulbright US LLP
- Main IPC: C07D305/00
- IPC: C07D305/00 ; C07D305/14 ; C07D407/12
Abstract:
Disclosed is a method of crystallizing a taxane comprising combining the taxane and methylene chloride to obtain a solution and adding an anti-solvent to the solution to obtain a crystalline taxane, wherein the anti-solvent is selected from the group consisting of hexane and heptane.
Public/Granted literature
- US20150005517A1 PURIFICATION OF TAXANES Public/Granted day:2015-01-01
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