Invention Grant
US09303032B2 2-(pyridin-2YL)-1, 7-diaza-spiro [4.4] nonane-6-one compound as voltage-gated sodium channels modulator
有权
2-(吡啶-2-基)-1,7-二氮杂 - 螺[4.4]壬烷-6-酮化合物作为电压门控钠通道调节剂
- Patent Title: 2-(pyridin-2YL)-1, 7-diaza-spiro [4.4] nonane-6-one compound as voltage-gated sodium channels modulator
- Patent Title (中): 2-(吡啶-2-基)-1,7-二氮杂 - 螺[4.4]壬烷-6-酮化合物作为电压门控钠通道调节剂
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Application No.: US14365391Application Date: 2012-12-21
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Publication No.: US09303032B2Publication Date: 2016-04-05
- Inventor: David R. Witty , David T. MacPherson , Gerard M. P. Giblin , Steven J. Stanway
- Applicant: CONVERGENCE PHARMACEUTICALS LIMITED
- Applicant Address: GB London
- Assignee: Convergence Pharmaceuticals Limited
- Current Assignee: Convergence Pharmaceuticals Limited
- Current Assignee Address: GB London
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Kathryn D. Doyle; Jonathan P. O'Brien
- Priority: GB1122113.2 20111222
- International Application: PCT/GB2012/053233 WO 20121221
- International Announcement: WO2013/093496 WO 20130627
- Main IPC: C07D487/10
- IPC: C07D487/10 ; C07D471/10
![2-(pyridin-2YL)-1, 7-diaza-spiro [4.4] nonane-6-one compound as voltage-gated sodium channels modulator](/abs-image/US/2016/04/05/US09303032B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to spiro derivative of formula (I), to the use of said derivative in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivative and processes for its preparation.
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