Invention Grant
- Patent Title: Methods useful in the synthesis of halichondrin B analogs
- Patent Title (中): 用于合成软组蛋白B类似物的方法
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Application No.: US14562086Application Date: 2014-12-05
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Publication No.: US09303039B2Publication Date: 2016-04-05
- Inventor: Huiming Zhang , Bryan M. Lewis
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Clark & Elbing LLP
- Main IPC: C07D321/00
- IPC: C07D321/00 ; C07D493/22
Abstract:
In general, the present invention features improved methods useful for the synthesis of analogs of halichondrin B, such as eribulin and pharmaceutically acceptable salts thereof (e.g., eribulin mesylate).
Public/Granted literature
- US20150158881A1 METHODS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS Public/Granted day:2015-06-11
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