Invention Grant
- Patent Title: 5-HT3 receptor antagonists
- Patent Title (中): 5-HT3受体拮抗剂
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Application No.: US14415712Application Date: 2013-07-16
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Publication No.: US09303045B2Publication Date: 2016-04-05
- Inventor: Stephen Hitchcock , Holger Monenschein , Holly Reichard , Huikai Sun , Shota Kikuchi , Todd Macklin , Maria Hopkins
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agent Matthew J. Russo; David M. Stemerick
- International Application: PCT/US2013/050762 WO 20130716
- International Announcement: WO2014/014962 WO 20140123
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D498/04 ; A61K31/537 ; C07D519/00 ; C07D498/08 ; C07D451/12 ; A61K31/19 ; A61K31/5386 ; C07D221/22
Abstract:
The present invention provides compounds of the formula: that are 5HT3 receptor antagonists and are therefore useful for the treatment of diseases treatable by inhibition of 5HT3 receptor such as emesis, pain, drug addiction, neurodegenerative and psychiatric disorders, and GI disorders. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
Public/Granted literature
- US20150291624A1 5-HT3 RECEPTOR ANTAGONISTS Public/Granted day:2015-10-15
Information query
