Invention Grant
US09303056B2 Monomer for synthesis of RNA, method for producing same, and method for producing RNA
有权
用于合成RNA的单体，其制备方法及其制备方法
- Patent Title: Monomer for synthesis of RNA, method for producing same, and method for producing RNA
- Patent Title (中): 用于合成RNA的单体，其制备方法及其制备方法
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Application No.: US14417244Application Date: 2013-07-25
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Publication No.: US09303056B2Publication Date: 2016-04-05
- Inventor: Masanori Kataoka
- Applicant: Kochi University
- Applicant Address: JP Kochi
- Assignee: Kochi University
- Current Assignee: Kochi University
- Current Assignee Address: JP Kochi
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2012-164985 20120725
- International Application: PCT/JP2013/070247 WO 20130725
- International Announcement: WO2014/017615 WO 20140130
- Main IPC: C12P19/44
- IPC: C12P19/44 ; C07H21/00 ; C07H21/02 ; C07H19/048 ; C07H19/20 ; C07H19/10 ; C07H19/06 ; C07H19/16 ; C07H1/00
Abstract:
The objective of the present invention is to provide a monomer for RNA synthesis which can be efficiently produced and therefore by which the producing cost of RNA can be remarkably decreased, and a method for efficiently producing the monomer in a small number of steps. In addition, the objective of the present invention is also to provide a method by which RNA can be efficiently produced even when a approximately stoichiometry amount of the monomer for RNA synthesis is used. The monomer for RNA synthesis according to the present invention is represented by the following formula (I) or (I′): wherein R1 is a protective group of the hydroxy group and R2 is an alkyl group or the like.
Public/Granted literature
- US20150210731A1 MONOMER FOR SYNTHESIS OF RNA, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING RNA Public/Granted day:2015-07-30
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