Invention Grant
- Patent Title: Methods and reagents for analyzing riboswitches using FRET
- Patent Title (中): 用FRET分析核糖开关的方法和试剂
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Application No.: US13459989Application Date: 2012-04-30
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Publication No.: US09303057B2Publication Date: 2016-04-05
- Inventor: Scott C. Blanchard , Ronald Micura , Andrea Haller
- Applicant: Scott C. Blanchard , Ronald Micura , Andrea Haller
- Applicant Address: US NY Ithaca AT Innsbruck
- Assignee: CORNELL UNIVERSITY,LEOPOLD-FRANZENS UNIVERSITAT INNSBRUCK
- Current Assignee: CORNELL UNIVERSITY,LEOPOLD-FRANZENS UNIVERSITAT INNSBRUCK
- Current Assignee Address: US NY Ithaca AT Innsbruck
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02 ; C12N15/115 ; G01N21/64
Abstract:
The present invention is provides isolated riboswitches with FRET pairs for distinguishing changes in regulatory interactions controlled by the expression platform domain found in riboswitches. The invention further provides methods of using those riboswitches to detect structural changes in the expression platform domain and to identify potential antibiotics.
Public/Granted literature
- US20120276646A1 METHODS AND REAGENTS FOR ANALYZING RIBOSWITCHES USING FRET Public/Granted day:2012-11-01
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