Invention Grant
- Patent Title: Immunogenic polypeptides comprising a scaffold polypeptide and a L2 polypeptide or a fragment thereof
- Patent Title (中): 包含支架多肽和L2多肽或其片段的免疫原性多肽
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Application No.: US13140793Application Date: 2009-12-17
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Publication No.: US09303082B2Publication Date: 2016-04-05
- Inventor: Martin Mueller , Ivonne Rubio , Massimo Tommasino , Simone Ottonello , Angelo Bolchi
- Applicant: Martin Mueller , Ivonne Rubio , Massimo Tommasino , Simone Ottonello , Angelo Bolchi
- Applicant Address: DE Heidelberg
- Assignee: DKFZ Deutsches Krebsforschungszentrum
- Current Assignee: DKFZ Deutsches Krebsforschungszentrum
- Current Assignee Address: DE Heidelberg
- Agency: Foley & Lardner LLP
- Priority: EP08172349 20081219
- International Application: PCT/EP2009/067422 WO 20091217
- International Announcement: WO2010/070052 WO 20100624
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/08 ; A61K39/12 ; C07K14/005 ; C12N7/00 ; A61K39/385 ; A61K39/00
Abstract:
The present invention relates to an immunogenic polypeptide comprising a) a scaffold polypeptide, and b) a L2 polypeptide or a fragment of said L2 polypeptide, wherein said scaffold polypeptide constrains the structure of said L2 polypeptide, or of a fragment of said L2 polypeptide. Moreover, the present invention relates to a vaccine comprising said immunogenic polypeptide. The present invention is also concerned with a method for producing an antibody against human papillomavirus. Also encompassed by the present invention is an antibody obtained by carrying out the said method.
Public/Granted literature
- US20110293621A1 IMMUNOGENIC POLYPEPTIDES COMPRISING A SCAFFOLD POLYPEPTIDE AND A L2 POLYPEPTIDE OR A FRAGMENT THEREOF Public/Granted day:2011-12-01
Information query
