Invention Grant
US09303088B2 Detecting and treating breast cancer resistance to EGFR inhibitors
有权
检测和治疗乳腺癌对EGFR抑制剂的抗性
- Patent Title: Detecting and treating breast cancer resistance to EGFR inhibitors
- Patent Title (中): 检测和治疗乳腺癌对EGFR抑制剂的抗性
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Application No.: US13248690Application Date: 2011-09-29
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Publication No.: US09303088B2Publication Date: 2016-04-05
- Inventor: Sun-Young Moonlee , Mina J. Bissell , Saori Furuta , Roland Meier , Paraic A. Kenny
- Applicant: Sun-Young Moonlee , Mina J. Bissell , Saori Furuta , Roland Meier , Paraic A. Kenny
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Knobbe Martens Olson & Bear LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/30
Abstract:
The application describes therapeutic compositions and methods for treating cancer. For example, therapeutic compositions and methods related to inhibition of FAM83A (family with sequence similarity 83) are provided. The application also describes methods for diagnosing cancer resistance to EGFR inhibitors. For example, a method of diagnosing cancer resistance to EGFR inhibitors by detecting increased FAM83A levels is described.
Public/Granted literature
- US20120094843A1 DETECTING AND TREATING BREAST CANCER RESISTANCE TO EGFR INHIBITORS Public/Granted day:2012-04-19
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