Invention Grant
US09303247B2 Proliferating agent for monocyte, culture medium for proliferating monocyte, method for producing monocyte, method for producing dendritic cell, and method for producing dendritic cell vaccine
有权
单核细胞增生剂,单核细胞增殖培养基,单核细胞生产方法,树突细胞的制备方法及树突状细胞疫苗的制备方法
- Patent Title: Proliferating agent for monocyte, culture medium for proliferating monocyte, method for producing monocyte, method for producing dendritic cell, and method for producing dendritic cell vaccine
- Patent Title (中): 单核细胞增生剂,单核细胞增殖培养基,单核细胞生产方法,树突细胞的制备方法及树突状细胞疫苗的制备方法
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Application No.: US14343240Application Date: 2013-02-08
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Publication No.: US09303247B2Publication Date: 2016-04-05
- Inventor: Hiroyuki Abe , Hiroaki Kawasaki
- Applicant: Hakushinkouseikai Foundation , Life Science Research Institute Ltd.
- Applicant Address: JP JP
- Assignee: HAKUSHINKOUSEIKAI FOUNDATION,LIFE SCIENCE RESEARCH INSTITUTE LTD.
- Current Assignee: HAKUSHINKOUSEIKAI FOUNDATION,LIFE SCIENCE RESEARCH INSTITUTE LTD.
- Current Assignee Address: JP JP
- Agency: Cantor Colburn LLP
- Priority: JP2012-027332 20120210
- International Application: PCT/JP2013/053154 WO 20130208
- International Announcement: WO2013/118899 WO 20130815
- Main IPC: C12N5/0786
- IPC: C12N5/0786 ; C12N5/0784 ; A61K39/00

Abstract:
The purpose of the present invention is to provide a means for proliferating a monocyte with high efficiency and in a simple manner. The present invention provides a proliferating agent for a monocyte, which consists of at least one component selected from Flt-3L, IL-3 and IFN-γ and can be used before a treatment for differentiation of a monocyte into a dendritic cell. The present invention also provides a culture medium for use in the proliferation of a monocyte, which contains at least one component selected from Flt-3L, IL-3 and IFN-γ and can be used before a treatment for differentiation of a monocyte into a dendritic cell. The culture medium for use in the proliferation of a monocyte according to the present invention may contain GM-CSF.
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