A method for operating a turbocharger arrangement of an internal combustion engine, the turbocharger arrangement comprising a low-pressure and a high-pressure turbocharging stage arranged sequentially, the low-pressure turbo-charging stage comprising a low-pressure turbine with a sensorless low-pressure turbine bypass valve, is provided. The method comprises evaluating at least one sensor signal of the turbocharger arrangement for detecting a failure mode of the sensorless low-pressure turbine bypass valve. In this way, the low-pressure turbine bypass valve may be monitored for degradation without utilizing a position sensor.