Invention Grant
- Patent Title: Molecular delivery with nanowires
- Patent Title (中): 分子传递与纳米线
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Application No.: US13264587Application Date: 2010-04-16
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Publication No.: US09304132B2Publication Date: 2016-04-05
- Inventor: Hongkun Park , EunGyeong Yang , Alexander K. Shalek , JinSeok Lee , Jacob Robinson , Amy Sutton , Myung-Han Yoon , Marsela Jorgolli
- Applicant: Hongkun Park , EunGyeong Yang , Alexander K. Shalek , JinSeok Lee , Jacob Robinson , Amy Sutton , Myung-Han Yoon , Marsela Jorgolli
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2010/031392 WO 20100416
- International Announcement: WO2010/121130 WO 20101021
- Main IPC: C12M1/00
- IPC: C12M1/00 ; C12Q1/68 ; G01N33/567 ; C12M1/34 ; C12N15/00 ; C12N15/74 ; C07H21/02 ; G01N31/22 ; G01N33/543 ; G01N33/50
Abstract:
A molecular delivery system including a plurality of nanowires (e.g., Si NWs), each of the nanowires having a surface layer formed of a silicon-containing material and a covalently bound linker (e.g., silane linker) attached to the surface layer, and optionally including a substrate to which the nanowires are adhered or a molecule to be delivered attached to the linker. Also disclosed is a method of delivering into a cell an exogenous molecule.
Public/Granted literature
- US20120094382A1 MOLECULAR DELIVERY WITH NANOWIRES Public/Granted day:2012-04-19
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