Invention Grant
US09304136B2 Means and methods for assessing increased peroxisomal proliferation
有权
评估增加的过氧化物酶体增殖的方法和方法
- Patent Title: Means and methods for assessing increased peroxisomal proliferation
- Patent Title (中): 评估增加的过氧化物酶体增殖的方法和方法
-
Application No.: US14152411Application Date: 2014-01-10
-
Publication No.: US09304136B2Publication Date: 2016-04-05
- Inventor: Bennard van Ravenzwaay , Werner Mellert , Eric Fabian , Volker Strauss , Tilmann B. Walk , Ralf Looser , Edgar Leibold , Hennicke Kamp , Georgia Coelho Palermo Cunha , Michael Manfred Herold , Jan C. Wiemer , Alexandre Prokoudine
- Applicant: BASF SE
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Agent Alison R. Scheidler; Roberte M. D. Makowski
- Priority: EP08157118 20080528; EP09151549 20090128
- Main IPC: G01N33/92
- IPC: G01N33/92 ; G01N33/68 ; G01N33/50 ; G01N33/82
Abstract:
The present invention pertains to the field of toxicological assessments for risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing increased peroxisomal proliferation. It also relates to a method of determining whether a compound is capable of inducing such peroxisomal proliferation in a subject and to a method of identifying a drug for treating increased peroxisomal proliferation. Furthermore, the present invention relates to a data collection including characteristic values of at least five metabolites, a data storage medium including data collection, and a system and a device for diagnosing increased peroxisomal proliferation. Finally, the present invention pertains to the use of a group of metabolites or means for the determination thereof for the manufacture of a diagnostic device or composition for diagnosing increased peroxisomal proliferation in a subject.
Public/Granted literature
- US20140186964A1 MEANS AND METHODS FOR ASSESSING INCREASED PEROXISOMAL PROLIFERATION Public/Granted day:2014-07-03
Information query
IPC分类:
