Systems and methods for selective authorization of code modules are provided. According to one embodiment, a kernel mode driver monitors events occurring within a file system or an operating system. Responsive to observation of a trigger event performed by or initiated by an active process, in which the active process corresponds to a first code module within the file system and the event relates to a second code module within the file system, performing or bypassing a real-time authentication process on the second code module with reference to a whitelist containing content authenticators of approved code modules, which are known not to contain viruses or malicious code. The active process is allowed to load the second code module into memory when the real-time authentication process is bypassed or when it is performed and determines a content authenticator of the code module matches one of the content authenticators.