A reception terminal and a method for compensating for inter-symbol interference (ISI) in a two-dimensional (2D) data structure are provided. The method for compensating for ISI includes transmitting, from a transmission terminal, a plurality of source pixel values based on a source 2D data structure via a channel, receiving, at a reception terminal, a plurality of pixel values for compensation based on a 2D data structure, and compensating each of the plurality of pixel values for compensation to each of corresponding pixel values after compensation. The plurality of pixel values for compensation are changed values of the pixel values of the source pixels due to the ISI, and each of the pixel values after compensation is determined based on both of each of the pixel values for compensation and values of adjacent pixels thereof.