Visual assistance systems and related methods are disclosed. A visual assistance system includes a visual assistance service configured to receive and display images from a user device on an electronic display for a live assistant. The visual assistance service is also configured to transmit assistant audio from the live assistant conveying information derived by the live assistant's review of the images. A visual assistance system comprises a user device configured to capture and transmit the images to the visual assistance service. The user device is also configured to receive the assistant audio from the visual assistance service, and reproduce the assistant audio to a user of the user device. The user is registered with the visual assistance service as having at least a minimum level of visual disability. A method of operating the visual assistance system includes receiving the images from, and transmitting the assistant audio to the user device.