An image sensor system that compensates the amplifier in a column of a pixel array. This uses a sampling capacitor, that receives a signal from a pixel of the pixel array. A first plate of the sampling capacitor receives a value from the amplifier representing an offset level of the amplifier. While receiving the offset level from the amplifier on the first plate, the capacitor receives information from the pixel on a second plate of the same capacitor that is receiving the offset, thereby canceling the offset. The value from said sampling capacitor indicative of said information from said pixel with said offset cancelled being coupled to said amplifier to amplify said value as a first pixel value. The amplifier is also connected to other selecting switches from other pixels of said column of the pixel array.