A drug-eluting medical filter having a conically shaped wire frame with a circular base and a plurality of bioabsorbable prongs extending at various positions around the periphery of the base toward a common apex. The prongs have a variable thickness along their length and contain bioactive material, such as heparin or other anti-platelet agent, etc. The bioactive material is varied in concentration along the length of the prongs depending on the need by the patient, and a protective or other coating can be applied on any portion of the frame and/or prongs.