Invention Grant
- Patent Title: Method for moderately increasing the proton conductivity of biological membranes with the aid of mitochondria-targeted delocalized cations
- Patent Title (中): 借助于线粒体靶向离域阳离子适度提高生物膜的质子传导率的方法
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Application No.: US13128966Application Date: 2008-11-12
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Publication No.: US09308214B2Publication Date: 2016-04-12
- Inventor: Vladimir P. Skulachev , Maxim V. Skulachev
- Applicant: Vladimir P. Skulachev , Maxim V. Skulachev
- Applicant Address: LU Luxembourg
- Assignee: MITOTECH S.A.
- Current Assignee: MITOTECH S.A.
- Current Assignee Address: LU Luxembourg
- Agency: Verrill Dana LLP
- Agent Wayne A. Keown
- International Application: PCT/RU2008/000706 WO 20081112
- International Announcement: WO2010/056145 WO 20100520
- Main IPC: A61K31/66
- IPC: A61K31/66 ; A61K31/352
Abstract:
The invention relates to biology and medicine, in particular, can be used in medicine for preparation of a pharmaceutical composition for specific, self-regulating uncoupling of mitochondria. The invention may be useful in treatment of diseases and conditions associated with violation of cellular metabolism, in treatment of obesity including its pathological forms, as well as in treatment of diseases associated with increased formation of free radicals and reactive oxygen species. In addition, the invention may be used in biotechnology for stimulation of growth of yeast and microorganisms as well as for stimulation of development of tissues and organs of plant and animal origin.
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