Invention Grant
- Patent Title: Compositions and methods for modulating EMT and uses thereof
- Patent Title (中): 用于调节EMT的组合物和方法及其用途
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Application No.: US13820396Application Date: 2011-08-30
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Publication No.: US09308238B2Publication Date: 2016-04-12
- Inventor: Christina Scheel , Robert A. Weinberg
- Applicant: Christina Scheel , Robert A. Weinberg
- Applicant Address: US MA Cambridge
- Assignee: Whitehead Institute for Biomedical Research
- Current Assignee: Whitehead Institute for Biomedical Research
- Current Assignee Address: US MA Cambridge
- Agency: Morse, Barnes-Brown & Pendleton, P.C.
- Agent Lisa M. Warren, Esq.
- International Application: PCT/US2011/049781 WO 20110830
- International Announcement: WO2012/030854 WO 20120308
- Main IPC: C12N5/00
- IPC: C12N5/00 ; A61K35/36 ; A61K38/18 ; A61K45/06
Abstract:
The invention provides compositions and methods useful for modulating epithelial-mesenchymal transition (EMT). Certain of the compositions and methods are useful for inducing epithelial cells to undergo an EMT. The invention further provides cells generated using the inventive methods and methods of use thereof. Certain of the compositions and methods are useful for inhibiting epithelial cells from undergoing an EMT. Certain of the compositions and methods are useful for inhibiting EMT in a subject in need thereof.
Public/Granted literature
- US20140010789A1 COMPOSITIONS AND METHODS FOR MODULATING EMT AND USES THEREOF Public/Granted day:2014-01-09
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