Invention Grant
US09309198B2 N-[3-(2-carboxyethyl)phenyl]piperidin-1-ylacetamide derivatives and use thereof as activators of soluble guanylate cyclase
有权
N- [3-(2-羧乙基)苯基]哌啶-1-基乙酰胺衍生物及其可用作可溶性鸟苷酸环化酶的活化剂
- Patent Title: N-[3-(2-carboxyethyl)phenyl]piperidin-1-ylacetamide derivatives and use thereof as activators of soluble guanylate cyclase
- Patent Title (中): N- [3-(2-羧乙基)苯基]哌啶-1-基乙酰胺衍生物及其可用作可溶性鸟苷酸环化酶的活化剂
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Application No.: US14402232Application Date: 2013-05-17
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Publication No.: US09309198B2Publication Date: 2016-04-12
- Inventor: Thomas Lampe , Michael Hahn , Johannes-Peter Stasch , Karl-Heinz Schlemmer , Frank Wunder , Sherif El Sheikh , Volkhart Min-Jian Li , Eva Maria Becker-Pelster , Friederike Stoll , Andreas Knorr
- Applicant: Bayer Pharma Aktiengesellschaft
- Applicant Address: DE Berlin
- Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee Address: DE Berlin
- Agency: Buchanan Ingersoll & Rooney
- Priority: DE102012208530 20120522
- International Application: PCT/EP2013/060222 WO 20130517
- International Announcement: WO2013/174736 WO 20131128
- Main IPC: C07D211/14
- IPC: C07D211/14 ; C07D217/04 ; C07D221/06 ; A61K31/445 ; A61K31/451 ; A61K31/472 ; C07D221/20 ; C07D211/06 ; C07D211/18 ; C07D211/46 ; C07D295/15 ; A61K31/438 ; A61K45/06
![N-[3-(2-carboxyethyl)phenyl]piperidin-1-ylacetamide derivatives and use thereof as activators of soluble guanylate cyclase](/abs-image/US/2016/04/12/US09309198B2/abs.jpg.150x150.jpg)
Abstract:
The present application relates to novel substituted 2-(piperidin-1-yl)acetamide derivatives, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of cardiovascular diseases.
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