- Patent Title: Macrocyclic urea and sulfamide derivatives as inhibitors of TAFIa
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Application No.: US14811364Application Date: 2015-07-28
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Publication No.: US09309207B2Publication Date: 2016-04-12
- Inventor: Christopher Kallus , Mark Broenstrup , Andreas Evers , Anja Globisch , Herman Schreuder , Michael Wagner
- Applicant: SANOFI
- Applicant Address: FR Paris
- Assignee: SANOFI
- Current Assignee: SANOFI
- Current Assignee Address: FR Paris
- Agency: Morrison & Foerster LLP
- Priority: EP08290520 20080606
- Main IPC: C07D269/00
- IPC: C07D269/00 ; C07D413/12 ; C07D267/00 ; C07D273/01 ; C07D273/02 ; C07D413/14 ; A61K31/395
Abstract:
The invention relates to compounds of the formula (I) which are inhibitors of activated thrombin-activable fibrinolysis inhibitor. The compounds of the formula I are suitable for producing medicaments for prophylaxis, secondary prevention and treatment of one or more disorders associated with thromboses, embolisms, hypercoagulability or fibrotic changes.
Public/Granted literature
- US20160024033A1 MACROCYCLIC UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIA Public/Granted day:2016-01-28
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