Invention Grant
US09309216B2 Process for preparation of optically pure and optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives and their use in preparing pharmaceuticals
有权
光学纯的和任选取代的2-(1-羟基 - 烷基) - 色烯-4-酮衍生物的制备方法及其在制备药物中的用途
- Patent Title: Process for preparation of optically pure and optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives and their use in preparing pharmaceuticals
- Patent Title (中): 光学纯的和任选取代的2-(1-羟基 - 烷基) - 色烯-4-酮衍生物的制备方法及其在制备药物中的用途
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Application No.: US14398902Application Date: 2013-05-03
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Publication No.: US09309216B2Publication Date: 2016-04-12
- Inventor: Jayaraman V. Raman , Swaroop K. Vakkalanka
- Applicant: Rhizen Pharmaceuticals SA
- Applicant Address: CH La Chaux-de-Fonds
- Assignee: RHIZEN PHARMACEUTICALS SA
- Current Assignee: RHIZEN PHARMACEUTICALS SA
- Current Assignee Address: CH La Chaux-de-Fonds
- Agency: Blank Rome LLP
- Priority: IN1737/CHE/2012 20120504
- International Application: PCT/IB2013/053544 WO 20130503
- International Announcement: WO2013/164801 WO 20131107
- Main IPC: C07D311/36
- IPC: C07D311/36 ; C07D405/06

Abstract:
The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceuticals. In particular, the present invention concerns enantiomerically pure optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives represented by formula (IA) and (IB), processes for preparing the alcohol derivatives and their use in preparing pharmaceuticals.
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