Invention Grant
US09309233B2 Compositions and methods for the treatment of blood clotting disorders 有权
用于治疗凝血障碍的组合物和方法

  • Patent Title: Compositions and methods for the treatment of blood clotting disorders
  • Patent Title (中): 用于治疗凝血障碍的组合物和方法
  • Application No.: US14399179
    Application Date: 2013-03-24
  • Publication No.: US09309233B2
    Publication Date: 2016-04-12
  • Inventor: Mahesh Kandula
  • Applicant: Mahesh Kandula
  • Applicant Address: IN Hyderabad, Telangana
  • Assignee: CELLIX BIO PRIVATE LIMITED
  • Current Assignee: CELLIX BIO PRIVATE LIMITED
  • Current Assignee Address: IN Hyderabad, Telangana
  • Agent Raj Abhyanker, P.C.
  • Priority: IN1809/CHE/2012 20120508
  • International Application: PCT/IB2013/052329 WO 20130324
  • International Announcement: WO2013/168025 WO 20131114
  • Main IPC: C07D235/14
  • IPC: C07D235/14 C07D409/12
Compositions and methods for the treatment of blood clotting disorders
Abstract:
The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II; and methods for treating or preventing blood clotting disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of strokes in those with atrial fibrillation due to causes other than heart valve disease, and at least one additional risk factor for stroke (congestive heart failure, hypertension, age, diabetes, and prior stroke), and to prevent the formation of blood clots in the veins in adults operated to replace a hip or knee.
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