Invention Grant
US09309247B2 2-substituted imidazo[4,5-D]phenanthroline derivatives and their use in the treatment of cancer
有权
2-取代咪唑并[4,5-D]菲咯啉衍生物及其在治疗癌症中的用途
- Patent Title: 2-substituted imidazo[4,5-D]phenanthroline derivatives and their use in the treatment of cancer
- Patent Title (中): 2-取代咪唑并[4,5-D]菲咯啉衍生物及其在治疗癌症中的用途
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Application No.: US14777198Application Date: 2014-03-20
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Publication No.: US09309247B2Publication Date: 2016-04-12
- Inventor: Yoon Lee , Howard Cukier , Venkata Nedunuri , Robert Peralta , Mario Huesca , Aiping H. Young
- Applicant: Aptose Biosciences Inc.
- Applicant Address: CA
- Assignee: LORUS THERAPEUTICS INC.
- Current Assignee: LORUS THERAPEUTICS INC.
- Current Assignee Address: CA
- Agency: Cooley LLP
- International Application: PCT/US2014/031349 WO 20140320
- International Announcement: WO2014/153464 WO 20140925
- Main IPC: A61K31/4745
- IPC: A61K31/4745 ; C07D471/12 ; C07D471/14
![2-substituted imidazo[4,5-D]phenanthroline derivatives and their use in the treatment of cancer](/abs-image/US/2016/04/12/US09309247B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides 2-substituted imidazo[4,5-d]phenanthroline compounds, which are capable of inhibiting proliferation of one or more renal cancer cells, pancreatic cancer cells, prostate cancer cells, colon cancer cells, leukemia cells, brain cancer/tumor cells or non-small cell lung cancer cells.
Public/Granted literature
- US20160031883A1 2-SUBSTITUTED IMIDAZO[4,5-D]PHENANTHROLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER Public/Granted day:2016-02-04
Information query
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