Invention Grant
US09309253B2 Tricyclic pyrrolo derivatives, process for their preparation and their use as kinase inhibitors
有权
三环吡咯衍生物，其制备方法及其作为激酶抑制剂的用途
- Patent Title: Tricyclic pyrrolo derivatives, process for their preparation and their use as kinase inhibitors
- Patent Title (中): 三环吡咯衍生物，其制备方法及其作为激酶抑制剂的用途
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Application No.: US14609534Application Date: 2015-01-30
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Publication No.: US09309253B2Publication Date: 2016-04-12
- Inventor: Marina Caldarelli , Mauro Angiolini , Italo Beria , Maria Gabriella Brasca , Francesco Casuscelli , Roberto D'Alessio , Andrea Lombardi Borgia
- Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
- Applicant Address: IT Nerviano (MI)
- Assignee: NERVIANO MEDICAL SCIENCES S.R.L.
- Current Assignee: NERVIANO MEDICAL SCIENCES S.R.L.
- Current Assignee Address: IT Nerviano (MI)
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP11152190 20110126
- Main IPC: A61K31/55
- IPC: A61K31/55 ; A61K45/06 ; C07D487/04 ; A61K31/519 ; C07C67/00 ; C07D207/34 ; C07D209/42 ; C07D401/04 ; C12N9/99
Abstract:
The present invention relates to tricyclic pyrrolo derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.
Public/Granted literature
- US20150141408A1 TRICYCLIC PYRROLO DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS Public/Granted day:2015-05-21
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