Invention Grant
US09309508B2 Boronic and borinic acid compound as inhibitors of sulfenic acid-containing proteins
有权
硼酸和硼酸化合物作为含亚磺酸蛋白质的抑制剂
- Patent Title: Boronic and borinic acid compound as inhibitors of sulfenic acid-containing proteins
- Patent Title (中): 硼酸和硼酸化合物作为含亚磺酸蛋白质的抑制剂
-
Application No.: US14576613Application Date: 2014-12-19
-
Publication No.: US09309508B2Publication Date: 2016-04-12
- Inventor: Stephen Benkovic , Chunyu Liu , John W. Tomsho
- Applicant: Stephen Benkovic , Chunyu Liu , John W. Tomsho
- Applicant Address: US PA University Park
- Assignee: THE PENN STATE RESEARCH FOUNDATION
- Current Assignee: THE PENN STATE RESEARCH FOUNDATION
- Current Assignee Address: US PA University Park
- Agency: Husch Blackwell, LLP
- Main IPC: C12N9/99
- IPC: C12N9/99 ; C12N9/88
Abstract:
A boronic or borinic acid compound is used to inhibit the activity of a sulfenic acid-containing protein. Thus, a biologically-active sulfenic acid-containing protein is contacted with an activity-inhibiting effective amount of a boronic or borinic acid compound of Formula I or a salt, hydrate or solvate thereof, whose components are disclosed within, and that contact is maintained for a time sufficient to inhibit the biological activity of the protein.
Public/Granted literature
- US20150140635A1 Boronic and Borinic Acid Compound as Inhibitors of Sulfenic Acid-Containing Proteins Public/Granted day:2015-05-21
Information query
