Invention Grant
- Patent Title: Molecular cloning of HIV-1 from immortalized cell lines
- Patent Title (中): 来自永生化细胞系的HIV-1的分子克隆
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Application No.: US08385231Application Date: 1995-02-08
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Publication No.: US09309574B1Publication Date: 2016-04-12
- Inventor: Robert C. Gallo , Flossie Wong-Staal , Mikulas Popovic , Beatrice H. Hahn , George M. Shaw , Amanda G. Fisher
- Applicant: Robert C. Gallo , Flossie Wong-Staal , Mikulas Popovic , Beatrice H. Hahn , George M. Shaw , Amanda G. Fisher
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agent Siegfried J. W. Ruppert; Susan S. Rucker
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/70
Abstract:
Disclosed is the molecular cloning of HTLV-III, the adult leukemia and acquired immune deficiency syndrome (AIDS) virus. Clone BH10 contains a 9.0 Kb viral insert constituting the entire HTLV-III genome. Clones BH8 and BH5 contain viral inserts of 5.5 Kb and 3.5 Kb, respectively. These clones are suitable for the development of diagnostic and therapeutic measures for AIDS, as well as use as probes for the detection of AIDS. By scientific convention, HTLV-III, referred to herein also as HIV, has been renamed as HIV-1.
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